Custom Peptides
Cayman Chemical Cefmetazole 10mg
A cephamycin antibiotic; active against E. coli, P. mirabilis, H. influenzae, N. gonorrhoeae, S. pneumoniae, and S. pyogenes (MIC50s = 0.25-2 μg/ml); decreases the lesion size and the number of ulcerative lesions in a rabbit model of active syphilis at 20 and 40 mg/kg per day
Cayman Chemical TetrahydrocurcumIn 10mg
A metabolite of curcumin with diverse biological activities; scavenges DPPH radicals in a cell-free assay (EC50 = 16.8 μM); inhibits LPS-induced increases in iNOS and COX-2 expression in RAW 264.7 cells at 50 µM; inhibits LPS-induced increases in TNF-α release at 100 µM; inhibits LPS-induced increases in NO production and IL-6 levels in a concentration-dependent manner; reduces carrageenan-induced paw edema in rats (ED50 = 20 mg/kg); reduces the formation of neocapillaries and decreases microvascular density as well as VEGF, VEGFR2, and HIF-1α expression in a CaSki cervical cancer nude mouse xenograft model at 100, 300, and 500 mg/kg
Cayman Chemical 7fluoro TryptamInhydrochl 10mg
A tryptamine derivative that potentially agonizes 5-HT serotonin receptors; intended for research and forensic applications
Cayman Chemical 2 NMethylperfluoroctnsul 10mg
A perfluoroalkyl substance; has been found in watersheds
Cayman Chemical W-7hydrochlorIde 10mg
A cell-permeable antagonist of calmodulin (Ki = 11 μM); also associates, at lower affinities, with calcium-binding domains of other proteins, including troponin C and myosin light chain kinase (Ki = 70 and 300 μM, respectively)
Cayman Chemical HexnoylCoenzyme AsodIum s 10mg
A medium-chain fatty acyl CoA; the preferred acyl donor substrate for GOAT; a precursor in the biosynthesis of olivetolic acid
Cayman Chemical PromestrIen 10mg
A synthetic estrogen; reduces vaginal atrophy and decreases in endometrial and myometrial wall thickness in ovariectomized rats when applied as a topical gel
Cayman Chemical N6-EthyladenosIn 10mg
An adenosine A1 and A3 receptor agonist; binds selectively to rat adenosine A1 and human adenosine A3 receptors over rat adenosine A2A and A3 receptors (Kis = 4.9, 4.7, 8,900 and 1,050 nM, respectively, for the recombinant receptors in CHO cells); inhibits forskolin-induced cAMP accumulation in CHO cells expressing the human recombinant adenosine A3 receptor at 10 µM
Cayman Chemical Desmethyl RnolazIn 10mg
An endogenous NOS inhibitor levels are increased in Dahl salt-sensitive rats fed a high-salt diet concomittant with an increase in blood pressure
Cayman Chemical 1 2DIoleoyl3Docosnoylrac 10mg
A triacylglycerol; has been found in cocoa butter and in CBEs containing shea stearin and palm mid fraction
Cayman Chemical ADL 08-0011hydrochlorIde 10mg
An active metabolite of alvimopan; a μ-opioid receptor antagonist (Ki = 0.25 nM); for μ-opioid receptors over κ- and δ-opioid receptors (Kis = 15.8 and 31.6 nM, respectively); inhibits endomorphin 1-induced inhibition of electrically induced contraction of isolated guinea pig ileum (pA2 = 9.4); reverses loperamide-induced delayed gastric emptying in a rat model of castor oil-induced diarrhea
Cayman Chemical EpIfrIedelnol 10mg
A triterpene with anticancer and senescence modifying activities; increases levels of P-gp and MDR2 and enhances doxorubicin-induced cytotoxicity in doxorubicin-resistant K562/ADM cells from 5-20 µM; inhibits doxorubicin-induced senescence in isolated HDFs, as well as replicative senescence in HDFs and HUVECs